Dimethylaminoethanol (DMAE) - Supplement Information
Supplement Information
Brain Function Enhancement!
When DMAE is used, the brain-function enhancement effects are remarkable. DMAE is a naturally occurring nutrient found in seafood such as anchovies and sardines, perhaps this explains why fish has often been called brain food.
DMAE has been reported as helping to elevate mood, improve memory and learning, heighten intelligence, increase physical energy and in laboratory animals, extended the life span. It is used by many people for its mild, safe, stimulant effect and yet DMAE also makes it easier for most people to get to sleep and to have more lucid dreams. Many people report less fatigue in the day and sounder sleep at night, as well as needing less sleep.
The stimulant effect of DMAE is significantly different from that produced by coffee, amphetamines, or other stimulant drugs: DMAE does not have a drug-like quick pick-up and quick come-down. people who take DMAE have reported that after three to four weeks they feel a mild stimulation continually, without side effects.
Learning, Behavior, and IQ
DMAE has proven to be a valuable and safe alternative for certain learning and behavior problems such as Attention Deficit Disorder (ADD) and hyperkinesia in children and adults. In one study, consisting of 25 girls and 83 boys, conducted by Dr. Carl pfeiffer of the Brain-Bio Center in princeton, New Jersey, DMAE was found to result in enhanced behavior in 2/3 of the boys and 3/4 of the girls. Hyperactivity was greatly lessened as attention span was lengthened, irritability was decreased, scholastic ability improved and in some cases, IQ was elevated.
What is it
DMAE is really one of the classic Smart Nutrients. It was discussed in the original Smart Drugs & Nutrients book. DMAE is an ingredient in some foods including anchovies.
What does it do
- Enhances "vigilance" (roughly translated, this means it makes you more alert and responsive to your environment and increases "presence of mind".)
- Elevates mood and learning.
- Improves memory.
- Increases intelligence.
- Extends the lifespan of laboratory animals.
- Increase physical energy.
- provides a mild, safe tonic effect.
- Makes it easier for most people to get to sleep.
- Enhances lucid dreams
- Decreases fatigue in the day while providing for sounder sleep at night.
- Reduces the need for sleep.
- Treatment for hyperactivity in children.
- Antiaging effects.
The body manufactures an important neurohormone called acetylcholine from the B vitamin choline, Acetylcholine is needed to convey motor and sensory signals from one nerve cell to the next along the nerve path. It also regulates the flow of nerve signals and is essential for all brain functions, especially memory. When there isn't enough acetylcholine in the brain and nerve cells, a person experiences symptoms ranging from depression, sluggish behavior, fatigue, slowed reflexes, muddled thinking, and poor memory to nervousness, anxiety and hyperkinetic behavior. When acetylcholine is adequately supplied, these disappear as brain and nerve functions are normalized. But when acetylcholine levels are further increased by supplementation, energy, reflexes, mental alertness, mood, memory, and learning ability often improve beyond the normal.
Despite good nutrition and plenty of dietary and supplemental choline, many people (perhaps up to 75% of the population) have acetylcholine deficiencies. This generally occurs because of membranous shields which keeps toxic waste products in the circulation from entering the brain and central nervous system can also block some necessary substances from gaining entry.
Choline must be converted by the liver into its lipid soluble form before it can cross these barriers and be turned into acetylcholine. If the body's ability to produce this form of choline is less than ideal, acetylcholine levels are likely to be low. There is an alternative way to increase acetylcholine, however, Dimethylaminoethanol (DMAE), also known as Deanol, is a safe, natural substance that easily crosses the barriers. In the brain and nerve cells it is converted first to choline and then to acetylcholine. In a sense DMAE may be regarded as a biochemical Trojan horse.
DMAE is a very efficient antioxidant and free-radical deactivator, it stabilizes lyposome membranes, preventing rupture of these scavenger bodies, which would result in leakage of collected toxins and protein-damaging enzymes. It reverses the formation of lipofuscin that causes the so-called aging spots or liver spots. This pigment also tends to clog brain and nerve cells as we age. DMAE also helps prevent sludging or clumping of red blood cells and makes more of them available for carrying oxygen to the tissues. DMAE also has several positive influences on red blood cells. It has been found that the addition of DMAE to whole blood stored for transfusion purposes doubles its storage life. When DMAE was added to the drinking water of mice that were already past their mean expected lifespan, their maximum lifespan was extended to 36.6% longer than the controls. This indicates that it may be one of the only life-extension substances that is significantly effective even when started late in life.
Because of its ability to improve muscle reflexes and increase oxygen efficiency, many top athletes now take DMAE to improve performance and gain a competitive edge.



